Assessment of the response to antiepileptic drugs in epileptic patients WITH structural lesion(S) on neuroimaging
نویسندگان
چکیده
منابع مشابه
Pharmacovigilance in epileptic patients using antiepileptic drugs.
OBJECTIVE To investigate the occurrence of adverse effects of antiepileptic drugs (AED) in chronic epileptic patients in mono or polytherapy. METHOD We evaluated consecutive patients that met the following inclusion criteria: age of 18 years or older, diagnosis of epilepsy for at least one year, stable dose of AED for at least three months. Patients were asked if they had any adverse event re...
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Background and purpose: Anti-epileptic drugs (AEDs) can affect cognitive functions. The purpose of this study was to investigate the effects of lamotrigine (LT) on cognitive functions of patients with epilepsy. Materials and methods: A study with retrospective cohort design was carried out in which we assessed cognitive functions of 20 IGE patients attending Sari Bu Ali Hospital, and 12 health...
متن کاملHyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
PURPOSE Older enzyme-inducing antiepileptic drugs (AEDs) may induce supraphysiologic plasma concentrations of total (t) homocysteine (Hcy). The aim of the present study was to investigate the effect of new AEDs on plasma tHcy levels. METHODS Patients 18-50 years of age, on AEDs monotherapy, with no other known cause of hyper-tHcy were enrolled. Plasma tHcy, folate, vitamin B(12), and AEDs lev...
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Gastrointestinal (GI) discomforts are among the most common side effects of antiepileptic drugs (AEDs) that might lead to discontinuation or irregular consumption of the drugs. This study was conducted to evaluate the frequency of GI side effects of different AEDs in intractable epileptic patients treated with single or multiple drugs. GI discomfort of 100 epileptic patients (aged 35-76 years) ...
متن کاملAntiepileptic Drugs and Mental Health Status of Patients with Epilepsy
Many patients with epilepsy suffer also from coexisting psychological problems. These mental co-morbidities have a significant impact on quality of life of patients with epilepsy. Recent studies have shown that although antiepileptic drugs (AEDs) treat epilepsy, they may increase risk of mental disorders in these patients . Due to the lack of adequate research in this area, we assess...
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ژورنال
عنوان ژورنال: Journal of the Neurological Sciences
سال: 2019
ISSN: 0022-510X
DOI: 10.1016/j.jns.2019.10.864